10 Dogs That Really Shouldn t Be Mixed with Chihuahuas

Great Dane

Mixing a Chihuahua with a Great Dane could result in significant health issues due to the extreme size difference, posing serious risks during both pregnancy and birth.

Siberian Husky

Huskies are energetic and strong, making them a poor match for the small, fragile Chihuahua. The vast difference in size and activity levels could be problematic.


The Bullmastiff's large size and potential for aggressive behavior can pose a danger to the tiny Chihuahua, especially if the mix inherits the Bullmastiff's protective nature.

Saint Bernard

Saint Bernards are massive and can unintentionally harm a Chihuahua due to their size and weight. The mix could also inherit health problems common to both breeds.


Malamutes are powerful and need lots of exercise, which contrasts sharply with the Chihuahua's small size and more moderate exercise needs, leading to potential mismatches in care requirements.


Rottweilers are known for their strength and guarding instincts, which could be dangerous if paired with the delicate Chihuahua, increasing the risk of accidental injury.


Greyhounds, though gentle, have a high prey drive, which might be problematic when mixed with a small dog like a Chihuahua. The size difference also poses risks.


Dalmatians are active and larger, requiring more space and exercise than a Chihuahua, making the combination potentially difficult to manage and care for properly.

Bernese Mountain Dog

These large, heavy dogs are not suited to be mixed with the small Chihuahua, as the size disparity could lead to serious health and safety concerns.


Dobermans are powerful and often used as guard dogs, which may not be a good fit with the Chihuahua s size and temperament, leading to potential behavioral and health issues.